Chronic, inflammatory, systemic disease which may cause joint or connective tissue damage & visceral lesions throughout the body characterised by fever, rash, hepato-spleenomegaly & arthritis in children.
It is a persistent inflammatory arthritis (6 weeks) that begins before age 16 for which no specific cause can be found.
• Exact cause is unknown.
• Evidence points to autoimmune aetiology.
• Associated with physical or emotional stress.
• Age: Under 16 years of age.
• Sex: Common in girls. Signs
• Fever: remittent.
• Rash on trunk, limbs as patches of erythema.
• Affected joints hot, tender & swollen.
• Effusion of joint.
• Limitation of joint movement.
INVESTIGATIONS for Juvenile Rheumatoid Arthritis
• Hb%: low.
• TLC: 20,000-50,000/cu.mm.
• DLC: increased polymorphs.
• Rheumatoid factor: positive (15%).
• ANA: positive (25%).
• Soft tissue swelling.
• Loss of joint space.
• Irregularity of joint surface.
• Periosteal new bone formation.
• Growth disturbance.